Can A Fish Teach Medicine?

Adam Wilson, M1, Class of 2026

How can a fish teach medicine, how does diabetes result from environmental contamination, and how does environmental contamination cause illness through biological and non-biological mechanisms? I recently read “The River Is in Us: Fighting Toxics in a Mohawk Community” by Elizabeth Hoover, which prompted these questions. Hoover describes the impact of contamination and disruption of a Native American community’s environment located at Akwesasne along the St. Lawrence Seaway and bisected by the U.S.-Canada border. Akwesasne is downwind and downriver from a few sites, such as Reynolds Metals and General Motors Central Foundry, recognized as particularly hazardous to human and environmental health by federal and state governments. As a foreword, the Mohawk community at Akwesasne has a long history that this article cannot do justice to. I highly recommend reading Hoover’s book for more information on historical and cultural contexts.

Sculpture by Akwesasne Mohawk artist Natasha Smoke Santiago, depicting a traditional Mohawk woman made from corn husks, insulin bottles, and hypodermic needles. This piece represents the rapid increase of cases of diabetes in the Akwesasne community, with the corn husks symbolizing the traditional foods that the artist wants her relatives to return to in order to regain their health. Photograph by Jessica Sargent. Caption by Elizabeth Hoover.

The Blue Hour

Anonymous

There’s a moment in the morning,

where the nocturnal sky begins to meet the new day,

a reunion of the dark night and the burning crimson sky. 

 

yet even before the celebration of the sun rising,

blue hues beginning to fill the streets,

a subtle and gentle awakening

 

Luster

Maddy Mash, MD Class of 2025

Stress, anxiety, heavy feelings, whatever you want to call it, come with a potency that overwhelms our mind, influencing every decision and the way we perceive the world. 

I have noticed I tend to look back on challenging stretches of life and think, that wasn’t so bad. Time gives us a lens with the blurring stress filter removed, giving a romanticized picture of the seemingly lackluster moments you overlooked. When this appreciation comes, all those moments are far gone, wasted on a overextended and burnt out mind probably because something wasn’t working out exactly the way we wanted it to at the time. 

RYR1

Vincent Czerwinski, M3, Class of 2024

RYR1 encodes the ryanodine receptor—a calcium channel found in skeletal muscles which opens in response to sarcolemma depolarization allowing calcium to move from the sarcoplasmic reticulum into the cytoplasm. Those with RYR1 mutations experience central core disease—a congenital myopathy characterized by profound muscular flaccidity. To a young medical student, this phenomenon is ‘interesting,’ a label reserved for the few and far between cases in medicine when a clear cellular mechanism produced intuitive effects phenotypically. However, no amount of intellectualization can prepare medical students for the sight of a four-year-old intubated girl sitting completely still in her room—the only movement coming from her eyes as she tracks the new presence in her space. Students may find this sight so uncanny that they quickly scan the patient’s medications to check for paralytics, already forgetting what they’ve just looked up regarding the effects of RYR1 mutations. 

Students are encouraged to push this unease aside and proceed with their duties, checking with the mother for overnight updates and performing a physical exam. They diligently collect data points for the all-important presentation: one of the many metrics by which students are measured.